Endocrine Abstracts

Introduction: Testosterone levels are frequently low in men with type two diabetes mellitus, and sexual symptoms are a prominent presenting feature for these men.Objectives: The aim of this study was to determine the frequency of hypogonadism and related risk factors among Tunisian patients with type two diabetes mellitus and erectile dysfunction.Methods: This cross–sectional study included a total of one hundred and thirty c...

IntroductionThe association between parathyroid and thyroid diseases is not uncommon; however concurrent presence of parathyroid adenoma and thyroid cancer is rare (1). As a natural consequence, preoperative imaging studies for diagnosis and localization of parathyroid adenomas may result with the detection of thyroid incidentalomas and most of these thyroid nodules should be evaluated by fine-needle aspiration biopsy before parathyroid surgery (1). We h...

Introduction: Hypoparathyroidism (HypoPT) is a rare endocrine disease characterized by abnormally low concentrations of PTH resulting in hypocalcemia. Etiologies are various and are dominated by postoperative HypoPT. HypoPT needs a lifelong treatment and follow-up in order to maintain appropriate calcium levels and prevent chronic complications.Patients and Methods: A retrospective descriptive study was conducted at the endocrinology department in Fattou...

Introduction : Primary adrenal lymphomas (PAL) are extremely rare and constitute 0.5% of all adrenal tumors. The number of cases described is approximately 70 cases [1] and It is bilaterally manifested in approximately 70% of cases [2]. The diagnosis is made on histological features, as there is no specific symptoms. Treatement is based on chemotherapy and prognosis is usually poor. We report two cases of bilateral PAL.Cases: First case: A 63-year-old wo...

Introduction: Precocious puberty (PP) is the development of secondary sexual characteristics before the age of 8 years in girls and beforethe age of 9 years in boys. Central PP has an idiopathic origin in upto 95% of girls while in up to 50% of males. The diagnostic and the management of PP can beparticularly complex. Here we describe cases of two sisters having central PP with different presentation and evolution.Observations: First case: A 13-years-old...

IntroductionSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel coronavirus that caused a global pandemic in 2020. The virus has infected more than 100 million people worldwide and the pandemic is still spreading. It can affect practically all organs. Data on the impact of SARSCoV-2 on the thyroid gland are very scarce. Two patients with Graves’ disease (GD) and COVID-19 have been recently published(1). We present a case GD occur...

Introduction: Congenital adrenal hyperplasia (CAH) due to an enzymatic defect in 11-beta-hydroxylase (11β-OHD) is the second most common cause of CAH representing 5-8% of cases. It is characterized by androgen excess, hypertension and hypokalemia. Here we describe the case of a patient having a CYP11B1 mutation and being followed-up during 33 years.Observation: A 36-year-old Tunisian male was diagnosed with 11β-OHD at the age of three years rev...